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李寒梅

职称:副研究员

最高学历毕业院校及专业:四川大学 药剂学

所属学科:药剂学

电子邮件:lihanmei@cdu.edu.cn

个人简历

研究方向

代表性论著

教学科研项目及获奖

职称 副研究员 最高学历毕业院校及专业 四川大学 药剂学
所属学科 药剂学 电子邮箱 lihanmei@cdu.edu.cn
研究方向 主要研究方向为抗感染药物靶向传递系统,具有生物响应性的智能释药系统及注射用缓释给药系统方面的研究。
发表论文
1. Hanmei Li, Dan Yin, Jiaying Liao, Yao Wang, Rui Gou, Chuane Tang, Wei Li, Yi Liu, Jiao Fu, Sanjun Shi, Liang Zou. Regulation of protein corona on liposomes using albumin-binding peptide for targeted tumor therapy. Journal of Controlled Release,2023,355:593-603. (中科院一区)

2.Hanmei Li, Qi Tang, Yao Wang, Mao Li, Yannan Wang, Hong Zhu, Fang Geng, Di Wu, Lianxin Peng, Gang Zhao, Liang Zou*, Sanjun Shi*. Injectable thermosensitive lipo-hydrogels loaded with ropivacaine for prolonging local anesthesia. International Journal of Pharmaceutics, 2022,121291.(Top期刊)


3. Hanmei Li, Yao Wang, Qi Tang, Dan Yin, Chuane Tang, En He a, Liang Zou∗, Qiang Peng*. The protein corona and its effects on nanoparticle-based drug delivery Systems. Acta Biomaterialia, 2021, 129: 57-72.(中科院一区)


4. Hanmei Li, Dan Yin, Wei Li, Qi Tang, Liang Zou, Qiang Peng. Polydopamine-based nanomaterials and their potentials in advanced drug delivery and therapy. Colloids and Surfaces B: Biointerfaces, 2021,199:111502.(TOP期刊)


5. Hanmei Li, Tao Liu, Yuxuan Zhu, Qiang Fu, Wanxia Wu, Jie Deng, Li Lan, Sanjun Shi*. An in situ-forming phospholipid-based phase transition gel prolongs the duration of local anesthesia for ropivacaine with minimal toxicity. Acta Biomaterialia, 2017, 58: 136-145.(中科院一区)


6. Hanmei Li, Yanping Li, Xue Wang, Yingying Hou, Xiaoyu Hong, Tao Gong, Zhirong Zhang, and Xun Sun*. Rational design of Polymeric Hybrid Micelles to Overcome Lymphatic and Intracellular Delivery Barriers in Cancer Immunotherapy. Theranostics, 2017, 7(18): 4383-4398.(中科院一区)


7. Hanmei Li, Yao Fu, Ting Zhang, Yanping Li, Xiaoyu Hong, Jiayu Jiang, Tao Gong, Zhirong Zhang, and Xun Sun*. Rational Design of Polymeric Hybrid Micelles with Highly Tunable Properties to Co-Deliver MicroRNA-34a and Vismodegib for Melanoma Therapy. Advanced functional materials, 2015, 48(25): 7457-7469.(中科院一区)


教学科研成果 主持国家自然科学基金项目2项,四川省科技项目2项;作为主要研究人员,参与完成国家级和省部级项目10余项;在国际知名期刊Acta Biomater.、Adv. Funct. Mater.、J. Control. Release等发表第一作者或通讯作者表论文20余篇;授权发明专利3件;获四川省高等教育教学成果奖一等奖1项。

1.基于生物正交反应和膜融合脂质体靶向修复血管内皮糖萼治疗急性肺损伤的研究,国家自然科学基金委面上项目;(主持)

2.基于蛋白冠调控实现肿瘤靶向的阳离子基因传递系统研究,国家自然科学基金委青年科学基金项目;(主持)

3.通过调控蛋白冠实现基因药物的肿瘤靶向递送,四川省应用基础研究项目;(主持)

4.内风湿关节炎的靶向治疗,成都大学高层次人才经费;(主持)

李寒梅,博士研究生,副教授。中国药学会理事、《中国抗生素杂志》青年编委。


主要研究方向为抗感染药物靶向传递系统,具有生物响应性的智能释药系统及注射用缓释给药系统方面的研究。

1. Hanmei Li, Dan Yin, Jiaying Liao, Yao Wang, Rui Gou, Chuane Tang, Wei Li, Yi Liu, Jiao Fu, Sanjun Shi, Liang Zou. Regulation of protein corona on liposomes using albumin-binding peptide for targeted tumor therapy. Journal of Controlled Release,2023,355:593-603. (中科院一区)
2.Hanmei Li, Qi Tang, Yao Wang, Mao Li, Yannan Wang, Hong Zhu, Fang Geng, Di Wu, Lianxin Peng, Gang Zhao, Liang Zou*, Sanjun Shi*. Injectable thermosensitive lipo-hydrogels loaded with ropivacaine for prolonging local anesthesia. International Journal of Pharmaceutics, 2022,121291.(Top期刊)
3. Hanmei Li, Yao Wang, Qi Tang, Dan Yin, Chuane Tang, En He a, Liang Zou∗, Qiang Peng*. The protein corona and its effects on nanoparticle-based drug delivery Systems. Acta Biomaterialia, 2021, 129: 57-72.(中科院一区)
4. Hanmei Li, Dan Yin, Wei Li, Qi Tang, Liang Zou, Qiang Peng. Polydopamine-based nanomaterials and their potentials in advanced drug delivery and therapy. Colloids and Surfaces B: Biointerfaces, 2021,199:111502.(TOP期刊)
5. Hanmei Li, Tao Liu, Yuxuan Zhu, Qiang Fu, Wanxia Wu, Jie Deng, Li Lan, Sanjun Shi*. An in situ-forming phospholipid-based phase transition gel prolongs the duration of local anesthesia for ropivacaine with minimal toxicity. Acta Biomaterialia, 2017, 58: 136-145.(中科院一区)
6. Hanmei Li, Yanping Li, Xue Wang, Yingying Hou, Xiaoyu Hong, Tao Gong, Zhirong Zhang, and Xun Sun*. Rational design of Polymeric Hybrid Micelles to Overcome Lymphatic and Intracellular Delivery Barriers in Cancer Immunotherapy. Theranostics, 2017, 7(18): 4383-4398.(中科院一区)
7. Hanmei Li, Yao Fu, Ting Zhang, Yanping Li, Xiaoyu Hong, Jiayu Jiang, Tao Gong, Zhirong Zhang, and Xun Sun*. Rational Design of Polymeric Hybrid Micelles with Highly Tunable Properties to Co-Deliver MicroRNA-34a and Vismodegib for Melanoma Therapy. Advanced functional materials, 2015, 48(25): 7457-7469.(中科院一区)

主持国家自然科学基金项目2项,四川省科技项目2项;作为主要研究人员,参与完成国家级和省部级项目10余项;在国际知名期刊Acta Biomater.、Adv. Funct. Mater.、J. Control. Release等发表第一作者或通讯作者表论文20余篇;授权发明专利3件;获四川省高等教育教学成果奖一等奖1项。
1.基于生物正交反应和膜融合脂质体靶向修复血管内皮糖萼治疗急性肺损伤的研究,国家自然科学基金委面上项目;(主持)
2.基于蛋白冠调控实现肿瘤靶向的阳离子基因传递系统研究,国家自然科学基金委青年科学基金项目;(主持)
3.通过调控蛋白冠实现基因药物的肿瘤靶向递送,四川省应用基础研究项目;(主持)
4.内风湿关节炎的靶向治疗,成都大学高层次人才经费;(主持)

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