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不对称催化方法学开发；药物的绿色合成方法开发

1. Qing-Zhu Li, Yi-Long Guan, Qian-Wei Huang, Ting Qi, Peng Xiang, Xiang Zhang, Hai-Jun Leng, Jun-Long Li* “Temperature-Controlled Divergent Asymmetric Synthesis of Indole-Based Medium-Sized Heterocycles through Palladium Catalysis”, ACS Catal. 2023, 13, 1164-1172. (IF: 13.7)
2. Qing-Zhu Li, Rong Zeng, Yang Fan, Yan-Qing Liu, Ting Qi, Xiang Zhang and Jun-Long Li*, “Remote C(sp3)−H Acylation of Amides and Cascade Cyclization via N-Heterocyclic Carbene Organocatalysis”, Angew. Chem. Int. Ed. 2022, 61, e202116629. (IF: 16.823)
3. Qing-Zhu Li, Yan-Qing Liu, Xin-Xin Kou, Wen-Lin Zou, Ting Qi, Peng Xiang, Jin-Dun Xing, Xiang Zhang and Jun-Long Li*, “Oxidative Radical NHC Catalysis: Divergent Difunctionalization of Olefins through Intermolecular Hydrogen Atom Transfer”, Angew. Chem. Int. Ed. 2022, 61, e202207824. (IF: 16.823)
4. Qing-Zhu Li, Xin-Xin Kou, Ting Qi, Jun-Long Li*, “Merging N-Heterocyclic Carbene Organocatalysis with Hydrogen Atom Transfer Strategy”, ChemCatChem 2022, DOI: 10.1002/cctc.202201320. (IF: 5.497, invited review)
5. Qing-Zhu Li, Wen-Lin Zou, Zhi-Qiang Jia, Jun-Long Li*, “Recent Advances on Annulation Reactions with Allyl and Propargyl Sulfonium Salts”, Synthesis 2022, 54, 67–78. (IF: 2.969, invited review)
6. Yang Fan#, Qing-Zhu Li#, Jun-Long Li*, Bin Zhang, Zhen Dai, Ke Xie, Rong Zeng, Liang Zou*, Xiang Zhang*, “Palladium-catalysed stereoselective [3 + 2] annulation of vinylethylene carbonates and tryptanthrin-based ketones”, Org. Chem. Front. 2022, 9, 197–203. (IF: 5.456)
7. Yan-Qing Liu#, Qing-Zhu Li#, Xin-Xin Kou, Rong Zeng, Ting Qi, Xiang Zhang, Cheng Peng, Bo Han, Jun-Long Li, “Radical Acylalkylation of 1,3-Enynes To Access Allenic Ketones via N‑Heterocyclic Carbene Organocatalysis”, J. Org. Chem. 2022, 87, 5229–5241. (IF: 4.198)
8. Qing-Zhu Li, Zhi-Qiang Jia, Lin Chen, Xiang Zhang, Hai-Jun Leng, Rong Zeng, Yan-Qing Liu, Wen-Lin Zou, Jun-Long Li*, “Construction of a Benzo[b]azepine Skeleton through Decarboxylative Ylide [6+1] Annulations with Modified VinylBenzoxazinanones”, Org. Lett. 2021, 23, 814–818. (IF: 6.072)
9. Hai-Jun Leng, Qing-Zhu Li*, Peng Xiang, Ting Qi, Qing-Song Dai, Zhi-Qiang Jia, Chuan Gou, Xiang Zhang, Jun-Long Li*, “Diastereoselective [3 + 1] Cyclization Reaction of Oxindolyl Azaoxyallyl Cations with Sulfur Ylides: Assembly of 3,3′-Spiro[β-lactam]-oxindoles” Org. Lett. 2021, 23, 1451–1456. (IF: 6.072)
10. Qing-Zhu Li, Rong Zeng, Bo Han*, Jun-Long Li*, “Single-Electron Transfer Reactions Enabled by N-Heterocyclic Carbene Organocatalysis”, Chem. Eur. J. 2021, 27, 3238. (IF: 5.02, invited review)
11. Jun-Long Li, Yan-Qing Liu, Wen-Lin Zou, Rong Zeng, Xiang Zhang, Yue Liu, Bo Han,* Hai-Jun Leng, Qing-Zhu Li*, “Radical Acylfluoroalkylation of Olefins through N-Heterocyclic Carbene Organocatalysis”, Angew. Chem. Int. Ed. 2020, 59, 1863–1870. (IF: 16.823)
12. Qing-Zhu Li, Yue Liu, Me-Ze Li, Xiang Zhang, Ting Qi, Jun-Long Li*, “Palladium-catalysed decarboxylative annulations of vinylethylene carbonates leading to diverse functionalised heterocycles”, Org. Biomol. Chem. 2020, 18, 3638. (IF: 3.89, invited review)
13. Hua Huang#, Qing-Zhu Li#, Yan-Qing Liu, Hai-Jun Leng, Peng Xiang, Qing-Song Dai, Xiang-Hong He, Wei Huang*, Jun-Long Li*, “Dearomative [4+2] annulations between 3-nitroindoles and enals through oxidative N-heterocyclic carbene catalysis”, Org. Chem. Front. 2020, 7, 3862–3867. (IF: 5.456)
14. Rong Zeng, Jun-Long Li*, Xiang Zhang, Yan-Qing Liu, Zhi-Qiang Jia, Hai-Jun Leng, Qian-Wei Huang, Yue Liu, Qing-Zhu Li*, “Diastereoselective Construction of 6,8-Dioxabicyclo[3.2.1]octane Frameworks from Vinylethylene Carbonates via Palladium-Organo Relay Catalysis”, ACS Catal., 2019, 9, 8256–8262. (IF:13.7)
15. Qing-Zhu Li, Xiang Zhang, Ke Xie, Qing-Song Dai, Rong Zeng, Yan-Qing Liu, Zhi-Qiang Jia, Xin Feng, Jun-Long Li*, “Diastereodivergent synthesis of cyclopropanes via on-water [2+1] annulations of diazo compounds with electron-deficient alkenes”, Green Chem., 2019, 21, 2375–2379. (IF: 11.034)
16. Qing-Zhu Li, Xiang Zhang, Rong Zeng, Qing-Song Dai, Yue Liu, Xu-Dong Shen, Hai-Jun Leng, Kai-Chuan Yang, Jun-Long Li*, “Direct Sulfide-Catalyzed Enantioselective Cyclopropanations of Electron-Deficient Dienes and Bromides”, Org. Lett., 2018, 20, 3700–3704. (IF: 6.072)
17. Xiang Zhang, Rong Zeng, Xin Feng, Qing-Song Dai, Yue Liu, Yan-Qing Liu, Qi-Wei Wang, Qing-Zhu Li*, Jun-Long Li*, “Intermolecular Cyclopropanation of Iodonium Ylides and Electron-Deficient Alkenes via a Highly Efficent Catalyst-free Process”, Asian J. Org. Chem., 2018, 7, 2065–2068. (IF: 3.319)
18. Qing-Zhu Li, Yue Liu, Hai-Jun Leng, Jun-Long Li*, “Asymmetric Construction of Halogenated Cyclic Quaternary Carbon Center through Enolate Activation of Aldehydes”, Synlett, 2018, 29, 2601–2607. (IF: 2.454, invited review)

1.主持国家自然科学基金面上项目：《氮杂环卡宾催化自由基历程的惰性键官能团化反应研究》，22071011， 2020－2024。
2.主持国家自然科学基金青年项目：《新型手性硫醚催化剂及其衍生物的设计合成与不对称催化应用研究》，21702021, 2018－2020。
3.主持四川省科技厅应用基础项目：《氮杂环卡宾催化的惰性键活化策略探索》2021YJ0404, 2021－2023。
4.主持抗生素研究与再评价四川省重点实验室开放课题：《运用新型氮杂环卡宾开发 抗感染先导药物的研究》，2018-2020。