拉斯维加斯(9888·VIP认证)游戏官网-Web Game Platform

师资队伍

辜玲慧

职称:副研究员

最高学历毕业院校及专业:四川大学 药物化学

所属学科:药物化学

电子邮件:cdglh017@163.com

个人简历

研究方向

代表性论著

教学科研项目及获奖

职称 副研究员 最高学历毕业院校及专业 四川大学 药物化学
所属学科 药物化学 电子邮箱 cdglh017@163.com
研究方向 过渡金属催化C-H官能团化及其新结构产物生物活性研究。 发表论文 1. Wenbo Ma*, Yuqiang Tan, Yang Wang, Zhiyi Li, Zheyu Li, Linghui Gu*, Ruhuai Mei, and An Cheng “Hydroxyl-Directed Ruthenium-Catalyzed peri-Selective C–H Acylmethylation and Annulation of Naphthols with Sulfoxonium Ylides”, Org. Lett. 2021, 16, 6200-6205. (IF: 6.1)

   2. Linghui Gu, Xinyue Fang, Zhengyun Weng, Jiafu Lin, Meicui He, Wenbo Ma*, “PIDA-Promoted Selective C5 C-H Selenylations of Indolines via Weak Interactions”, Adv. Synth. Catal., 2019, 361, 4998– 5004. (IF: 5.8)

3. Meicui He, Linghui Gu+, Yuqiang Tan, Yang Wang, Yuchi Wang, Chunran Zhang, Wenbo Ma* “Palladium-Catalyzed Distal C-H Selenylation of 2-Aryl Acetamides with Diselenides and Selenyl Chlorides”, Adv. Synth. Catal. 2020, 362, 5708– 5715. (IF: 5.8)

4. Wenbo Ma*, Yang Wang, Bo Li, Yunhao Zhou, Yue Xu, Yanan Sun, Linghui Gu*, An Cheng, “Rhodium-Catalyzed Oxidative Coupling of Potassium Vinyltrifluoroborate with Arenes: A Direct Access to Functionalized Styrene Derivatives”, Adv. Synth. Catal. 2022, 364, 3881– 3887. (IF: 5.8)

5. Linghui Gu, Xinyue Fang, Zhengyun Weng, Yupin Song, Wenbo Ma*, “Ligand- Free Palladium(II)‐Catalyzed ortho-C-H Chalcogenations of N-Arylsulfonamide via Weak Coordination”, Eur. J. Org. Chem. 2019, 1825–1829. (IF: 3.3)

6. Linghui Gu, Yang Wang, Zemin Cheng, Yanan Sun, Xin Gong, Zheyu Li, Wenbo Ma*, “Brønsted Acid Promoted N-Dealkylation of N-Alkyl(sulfon) amides”, ChemistrySelect , 2021, 6, 8839 –8842. (IF: 2.3)

7. Feng Xiong, Bo Li, Chenrui Yang, Liang Zou, Wenbo Ma, Linghui Gu*, Ruhuai Mei*, Lutz Ackermann*, “Copper-mediated oxidative C−H/ N−H activations with alkynes by removable hydrazides”, Beilstein J. Org. Chem. 2021, 17, 1591–1599. (IF: 2.5)

8. Shi-Lu Zheng, Yun-Xiang Zou, Zhong Wen, Jia-Fu Lin, Ling-Hui Gu*, Long Chen*, “Y(OTf )3-catalyzed phosphorylation of 2H-chromene hemiacetals with P(O)–H compounds to 2-phosphorylated 2H-chromenes”, Org. Biomol. Chem., 2021, 19, 6812–6816. (IF: 3.9)
教学科研成果 纵向课题:

1.主持四川省科技厅应用基础项目:《过渡金属钌催化依布硒啉衍生物的绿色合成及其在抗菌药物中的应用》,2022NSFSC0623,2022-2023。

2.主持抗生素研究与再评价四川省重点实验室开放课题项目:《铜催化新型磺胺芳基硒醚类化合物合成新方法及其抗肿瘤活性研究》,ARRLKF17-04 ,2017-2020。

3.参与四川省科技厅应用基础项目:《膦酰基取代杂环化合物的不对称催化构建及生物活性筛选》,2022NSFSC0625,2022-2023。

4.参与四川省科技厅应用基础项目:《锰催化氮杂䓬类化合物的合成及抗菌活性筛选》,2018JY0247,2018-2020。

授权专利:

1. 一种加强的乙酰苯胺类化合物的制备方法。2019,中国专利ZL201710482392.3

2. 硒/硫化磺酰芳胺类化合物及其硒/硫化方法。2021,中国专利ZL201811332588.5

辜玲慧,博士研究生,副研究员。

获奖或荣誉称号

入选2018年度“成华英才计划”紧缺人才项目,授予“成华英才”称号。

成都大学2020,2021年度优秀教师。


过渡金属催化C-H官能团化及其新结构产物生物活性研究。

1. Wenbo Ma*, Yuqiang Tan, Yang Wang, Zhiyi Li, Zheyu Li, Linghui Gu*, Ruhuai Mei, and An Cheng “Hydroxyl-Directed Ruthenium-Catalyzed peri-Selective C–H Acylmethylation and Annulation of Naphthols with Sulfoxonium Ylides”, Org. Lett. 2021, 16, 6200-6205. (IF: 6.1)
2. Linghui Gu, Xinyue Fang, Zhengyun Weng, Jiafu Lin, Meicui He, Wenbo Ma*, “PIDA-Promoted Selective C5 C-H Selenylations of Indolines via Weak Interactions”, Adv. Synth. Catal., 2019, 361, 4998– 5004. (IF: 5.8)
3. Meicui He, Linghui Gu+, Yuqiang Tan, Yang Wang, Yuchi Wang, Chunran Zhang, Wenbo Ma* “Palladium-Catalyzed Distal C-H Selenylation of 2-Aryl Acetamides with Diselenides and Selenyl Chlorides”, Adv. Synth. Catal. 2020, 362, 5708– 5715. (IF: 5.8)
4. Wenbo Ma*, Yang Wang, Bo Li, Yunhao Zhou, Yue Xu, Yanan Sun, Linghui Gu*, An Cheng, “Rhodium-Catalyzed Oxidative Coupling of Potassium Vinyltrifluoroborate with Arenes: A Direct Access to Functionalized Styrene Derivatives”, Adv. Synth. Catal. 2022, 364, 3881– 3887. (IF: 5.8)
5. Linghui Gu, Xinyue Fang, Zhengyun Weng, Yupin Song, Wenbo Ma*, “Ligand- Free Palladium(II)‐Catalyzed ortho-C-H Chalcogenations of N-Arylsulfonamide via Weak Coordination”, Eur. J. Org. Chem. 2019, 1825–1829. (IF: 3.3)
6. Linghui Gu, Yang Wang, Zemin Cheng, Yanan Sun, Xin Gong, Zheyu Li, Wenbo Ma*, “Brønsted Acid Promoted N-Dealkylation of N-Alkyl(sulfon) amides”, ChemistrySelect , 2021, 6, 8839 –8842. (IF: 2.3)
7. Feng Xiong, Bo Li, Chenrui Yang, Liang Zou, Wenbo Ma, Linghui Gu*, Ruhuai Mei*, Lutz Ackermann*, “Copper-mediated oxidative C−H/ N−H activations with alkynes by removable hydrazides”, Beilstein J. Org. Chem. 2021, 17, 1591–1599. (IF: 2.5)
8. Shi-Lu Zheng, Yun-Xiang Zou, Zhong Wen, Jia-Fu Lin, Ling-Hui Gu*, Long Chen*, “Y(OTf )3-catalyzed phosphorylation of 2H-chromene hemiacetals with P(O)–H compounds to 2-phosphorylated 2H-chromenes”, Org. Biomol. Chem., 2021, 19, 6812–6816. (IF: 3.9)

纵向课题:
1.主持四川省科技厅应用基础项目:《过渡金属钌催化依布硒啉衍生物的绿色合成及其在抗菌药物中的应用》,2022NSFSC0623,2022-2023。
2.主持抗生素研究与再评价四川省重点实验室开放课题项目:《铜催化新型磺胺芳基硒醚类化合物合成新方法及其抗肿瘤活性研究》,ARRLKF17-04 ,2017-2020。
3.参与四川省科技厅应用基础项目:《膦酰基取代杂环化合物的不对称催化构建及生物活性筛选》,2022NSFSC0625,2022-2023。
4.参与四川省科技厅应用基础项目:《锰催化氮杂䓬类化合物的合成及抗菌活性筛选》,2018JY0247,2018-2020。
授权专利:
1. 一种加强的乙酰苯胺类化合物的制备方法。2019,中国专利ZL201710482392.3
2. 硒/硫化磺酰芳胺类化合物及其硒/硫化方法。2021,中国专利ZL201811332588.5

XML 地图