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王建

职称:特聘研究员

最高学历毕业院校及专业:四川大学 有机化学

所属学科:药物化学

电子邮件:wj221471@163.com

个人简历

研究方向

代表性论著

教学科研项目及获奖

职称 特聘研究员 最高学历毕业院校及专业 四川大学 有机化学
所属学科 药物化学 电子邮箱 wj221471@163.com
研究方向 新型有机自由基反应的开发及其在药物分子合成中的应用。包括光催化、铁催化等绿色有机合成方法的开发,以及新型药物活性小分子的合成与性质研究。

发表论文 1.Jian Wang.* Transition-metal-free, visible-light-induced multicomponent synthesis of allylic amines and tetrahydroquinolines. Org. Chem. Front. 2022, 9, 3452-3459.

2.Jian Wang, Changqing Tu, Mei-Lin Feng, and Nan Li.* TEMPO/PhI(OAc)2- mediated Direct Sulfoximination of Benzoxazoles under Metal-free Conditions. Chem. Lett. 2022, 51, 756-759.

3.Jian Wang, Jiang-Hua Li, Yidong Guo, Hongbo Dong, Qiang Liu,* and Xiao-Qi Yu.* TEMPO-Mediated C–H Amination of Benzoxazoles with N-Heterocycles. J. Org. Chem. 2020, 85, 12797-12803.

4.Jian Wang,* and Wen-Jing Yi. Practical N-Hydroxyphthalimide-Mediated Oxidation of Sulfonamides to N-Sulfonylimines. Molecules. 2019, 24, 3771-3779.

5.Jian Wang, Gakhyun Kim, María Eugenia Sandoval-Salinas, Hoa Phan, Yadagiri Gopalakrishna Tullimi, Xuefeng Lu, David Casanova,* Dongho Kim,* Jishan Wu*. Stable 2D anti-ferromagnetically coupled fluorenyl radical dendrons. Chemical Science, 2018, 9, 3395-3400.

6.Jian Wang, Xingdong Xu, Hoa Phan, Tun Seng Herng, Tullimilli Y. Gopalakrishna, Guangwu Li, Jun Ding, Jishan Wu*. Stable Oxindolyl-Based Analogues of Chichibabin`s and Müller`s Hydrocarbons. Angew. Chem. Int. Ed. 2017, 56, 14154-14158.

7.Jian Wang, Xiao-Zhuan Zhang, Shan-Yong Chen, and Xiao-Qi Yu.* Iron-catalyzed Arylation or Aroylation of Benzothiazoles with Benzylic Alcohols and Aryl Ketones. Tetrahedron 2014, 70, 245-250.

8.Jian Wang, Shan Wang, Gao Wang, Ji Zhang and Xiao-Qi Yu.* Iron-mediated direct arylation with arylboronic acids through an arylradical transfer pathway. Chem. Commun. 2012, 48, 11769–11771.

9.Jian Wang, Ji-Ting Hou, Jun Wen, Ji Zhang and Xiao-Qi Yu.* Iron-catalyzed direct amination of azoles using formamides or amines as nitrogen sources in air. Chem. Commun. 2011, 47, 3652–3654.
教学科研成果 1.任教研究生课程《有机化学反应机理》和本科课程《药物合成综合实验》。

2.主持四川省自然科学基金项目(青年科学基金项目)一项,《低毒性对苯二腈作氰源的自由基氰基化反应研究》,2022NSFSC1252

3.主持横向项目一项,《氮杂卡宾类有机小分子的合成与开发    》

16706

王建,博士研究生,特聘研究员。

海外学习经历:2015年-2017年,新加坡国立大学化学学院从事博士后研究。


新型有机自由基反应的开发及其在药物分子合成中的应用。包括光催化、铁催化等绿色有机合成方法的开发,以及新型药物活性小分子的合成与性质研究。

1.Jian Wang.* Transition-metal-free, visible-light-induced multicomponent synthesis of allylic amines and tetrahydroquinolines. Org. Chem. Front. 2022, 9, 3452-3459.
2.Jian Wang, Changqing Tu, Mei-Lin Feng, and Nan Li.* TEMPO/PhI(OAc)2- mediated Direct Sulfoximination of Benzoxazoles under Metal-free Conditions. Chem. Lett. 2022, 51, 756-759.
3.Jian Wang, Jiang-Hua Li, Yidong Guo, Hongbo Dong, Qiang Liu,* and Xiao-Qi Yu.* TEMPO-Mediated C–H Amination of Benzoxazoles with N-Heterocycles. J. Org. Chem. 2020, 85, 12797-12803.
4.Jian Wang,* and Wen-Jing Yi. Practical N-Hydroxyphthalimide-Mediated Oxidation of Sulfonamides to N-Sulfonylimines. Molecules. 2019, 24, 3771-3779.
5.Jian Wang, Gakhyun Kim, María Eugenia Sandoval-Salinas, Hoa Phan, Yadagiri Gopalakrishna Tullimi, Xuefeng Lu, David Casanova,* Dongho Kim,* Jishan Wu*. Stable 2D anti-ferromagnetically coupled fluorenyl radical dendrons. Chemical Science, 2018, 9, 3395-3400.
6.Jian Wang, Xingdong Xu, Hoa Phan, Tun Seng Herng, Tullimilli Y. Gopalakrishna, Guangwu Li, Jun Ding, Jishan Wu*. Stable Oxindolyl-Based Analogues of Chichibabin`s and Müller`s Hydrocarbons. Angew. Chem. Int. Ed. 2017, 56, 14154-14158.
7.Jian Wang, Xiao-Zhuan Zhang, Shan-Yong Chen, and Xiao-Qi Yu.* Iron-catalyzed Arylation or Aroylation of Benzothiazoles with Benzylic Alcohols and Aryl Ketones. Tetrahedron 2014, 70, 245-250.
8.Jian Wang, Shan Wang, Gao Wang, Ji Zhang and Xiao-Qi Yu.* Iron-mediated direct arylation with arylboronic acids through an arylradical transfer pathway. Chem. Commun. 2012, 48, 11769–11771.
9.Jian Wang, Ji-Ting Hou, Jun Wen, Ji Zhang and Xiao-Qi Yu.* Iron-catalyzed direct amination of azoles using formamides or amines as nitrogen sources in air. Chem. Commun. 2011, 47, 3652–3654.

1.任教研究生课程《有机化学反应机理》和本科课程《药物合成综合实验》。
2.主持四川省自然科学基金项目(青年科学基金项目)一项,《低毒性对苯二腈作氰源的自由基氰基化反应研究》,2022NSFSC1252
3.主持横向项目一项,《氮杂卡宾类有机小分子的合成与开发 》

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